Substrate: Retinoic acid receptor RXR-alpha (Retinoic acid receptor RXR-alpha)
Seq-ID: P19793 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
MINT-24895   RARA_HUMAN
MINT-61590   SMAD2_HUMAN
MINT-61758   KPCD2_HUMAN
MINT-5224970   NCOA1_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein heterodimerization activity,
retinoid-X receptor activity,
transcription coactivator activity,
zinc ion binding,
sequence-specific DNA binding transcription factor activity,
ligand-regulated transcription factor activity,
vitamin D receptor binding,
steroid hormone receptor activity		 nucleus negative regulation of gene-specific transcription from RNA polymerase II promoter,
transcription,
vitamin metabolic process,
interspecies interaction between organisms,
response to retinoic acid,
cholesterol metabolic process
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 21 FSTQVNSSLTSPTGRGSMAAP - 18669648
HTP
0.30
 - -
0.76
 --
S 32 PTGRGSMAAPSLHPSLGPGIG - 16184197
LTP
0.15
 - -
0.78
 --
T 82 MGPHSMSVPTTPTLGFSTGSP MAPK_group 12048211
LTP
0.39
 MOD_ProDKin_1
 - -
0.67
 --
Y 249 ELAVEPKTETYVEANMGLNPS MAP2K4 10938283
LTP
0.32
 - -
0.52
 1FM6 32.75%
S 260 VEANMGLNPSSPNDPVTNICQ MAPK1 12048211
LTP
0.67
 MOD_ProDKin_1
 - -
0.53
 1FM6 60.66%
S 260 VEANMGLNPSSPNDPVTNICQ MAPK3 12048211
LTP
0.67
 MOD_ProDKin_1
 - -
0.53
 1FM6 60.66%
S 260 VEANMGLNPSSPNDPVTNICQ MAPK_group 10377179
LTP
0.67
 MOD_ProDKin_1
 - -
0.53
 1FM6 60.66%

Substrate: Retinoic acid receptor RXR-alpha (Retinoic acid receptor RXR-alpha)
Seq-ID: P28700 [Mus musculus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-25022   RARA_HUMAN
MINT-3374311   THA_MOUSE
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
retinoid-X receptor activity,
zinc ion binding,
sequence-specific DNA binding transcription factor activity,
steroid hormone receptor activity		 nucleus positive regulation of gene-specific transcription from RNA polymerase II promoter,
transcription,
cardiac muscle cell proliferation,
secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development,
ventricular cardiac muscle cell differentiation,
ventricular cardiac muscle tissue morphogenesis,
regulation of branching involved in prostate gland morphogenesis
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 22 STQVNSSSLNSPTGRGSMAVP - 10383391
LTP
0.42
 - -
0.75
 --
S 61 QLHSPISTLSSPINGMGPPFS - 10383391
LTP
0.72
 - -
0.55
 --
S 75 GMGPPFSVISSPMGPHSMSVP - 10383391
LTP
0.57
 - -
0.60
 --
T 87 MGPHSMSVPTTPTLGFGTGSP - 10383391
LTP
0.23
 - -
0.68
 --
S 265 VEANMGLNPSSPNDPVTNICQ - 10383391
LTP
0.61
 - -
0.53
 1FM6 60.66%

Valid HTML 4.01 Transitional